The basic position of Consumers Union urges FDA to recognize that nanoscale particles exhibit novel properties and/or behaviors, compared to their larger counterparts, and raise unique safety concerns, so that a separate safety assessment must be required before such nanoscale particles/materials can be used for any food ingredient or packaging component that comes in contact with food. We, thus, agree with the recommendation of the UK Royal Society, and the European Commission’s expert panel, which have stated that nanoparticles should be considered different that the normal size counterparts and separate safety assessments should be performed on them.